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While the calculator is not intended for clinical or personal use, it demonstrates how doses in clinical trials translate into measurable laboratory quantities

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[12] Very high cumulative exposure over months may encourage calcium deposition in soft tissues such as the renal parenchyma or coronary arteries, an outcome implicated in observational studies linking supra-physiological 25-hydroxyvitamin D levels with vascular calcification and heightened fracture risk in frail elders

And yet they're often what's driving the ongoing symptoms even after the bacterial load has been reduced