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You shouldnt take these medications if you: Are pregnant, breastfeeding, or trying to get pregnant Have a family or personal history of medullary thyroid cancer or multiple endocrine neoplasia type 2 (MEN 2) Have a known allergy to any ingredients in the medication Have a personal or family history of pancreatitis GLP-1 agonists cost and accessibility While these drugs can be highly effective, they can also be expensive

Neurol Sci Neurophysiol 41(1):2333

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Proponents of combining NAD+ supplementation with tirzepatide suggest several theoretical benefits, though it is crucial to emphasize that these potential synergies are largely speculative and not supported by clinical trial evidence