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The first cardiovascular study of NNMT enzyme inhibition in a heart failure with preserved ejection fraction (HFpEF) mouse model demonstrated that treatment markedly reduced 1-MNA (by 77.1%), 2PY (by 66.2%), and 4PY (by 71.1%) in cardiac tissue, while improving cardiac function, enhancing global longitudinal strain, reversing peak longitudinal strain rate, and significantly reducing left ventricular hypertrophy and fibrosis

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S., Stepp, M

Codes that may apply include K13.7 (other and unspecified lesions of oral mucosa), L81.9 (disorder of pigmentation, unspecified), or codes specific to the diagnosed underlying condition such as E27.1 for Addison's disease