Mechanisms and metabolic implications of regional differences among fat depots
It is characterised by small dysmorphic mitochondria with decreased cristae and condensed and ruptured outer membranes and is closely related to iron, polyunsaturated fatty acid, and amino acid metabolism, and glutathione, phospholipid, coenzyme Q10, and NADPH biosynthesis [6, 7]
Qian, G., Zhang, Y., Liu, Y., Li, M., Xin, B., Jiang, W., Han, W., Wang, Y., Tang, X., Li, L., Zhu, L., Sun, T., Yan, B., Zheng, Y., Xu, J., Ge, B., Zhang, Z., & Yan, D
myalgic encephalomyelitis chronic fatigue syndrome long COVID chronic illness medications pharmacotherapy supplements complementary therapies integrative medicine clinical practice patterns primary care specialists practice-based research INTRODUCTION Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a multisystem neurologic disease characterized by the following 2015 criteria of the National Academy of Medicine: (1) profound fatigue/reduction in function of at least 6 months, (2) postexertional malaise, (3) unrefreshing sleep, and (4) cognitive changes and/or orthostatic intolerance
