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Kevin J Lenton, Alain T San, Hlne Therriault, Andr M Cantin, Hlne Payette, J Richard Wagner - Vitamin C augments lymphocyte glutathione in subjects with ascorbate deficiency - Am J Clin Nutr - 2003 Jan

H and E and MF stained sections obtained from right sides of both groups, showed that 3 (30%) cases in group 1 and one (11.1%) case in group 2 were of epidermal type (showing increased density of melanin deposition in the basal and supra basal layers)

These investigations have examined the compound's biochemical effects in cultured cells and animal models as part of broader research into NNMT and cellular metabolism Importantly, these findings relate to preclinical research and should not be interpreted as evidence of established clinical efficacy, safety or therapeutic benefit in humans