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Four of those trials were double-blinded and placebo-controlled: STEP 1 (N = 1,950, randomized 2:1, semaglutide to placebo), STEP 2 (N = 1,210, randomized 1:1:1 to semaglutide 1.0 mg, semaglutide 2.4 mg, or placebo weekly), STEP 3 (N = 611, randomized 2:1, semaglutide to placebo), and STEP 4 (N = 803, randomized 1:1, semaglutide to placebo)

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