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The FDA does not have a formal legal category called bio-better. A bio-better is an improved biologic that files a full Biologics License Application (BLA) as a new molecular entity under Section 351(a) of the Public Health Service Act, rather than as a biosimilar under the abbreviated 351(k) pathway created by BPCIA

Scientists engineered tirzepatide to mimic naturally occurring incretin hormones while remaining active in the body for extended periods

The gentle formula helps reduce post-treatment swelling , making it an appealing choice for those with busy schedules

Potential reasons for this include: (1) 79% of our patients used a GLP-1 RA for an indication of diabetes rather than weight management, and (2) interactions with breast cancer treatments such as chemotherapy, chemotherapy supportive medications such as steroids, and/or endocrine therapy, which exacerbate metabolic dysfunction and contribute to weight gain, may attenuate weight loss with a GLP-1 RA