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10.5772/50095 29 RaschiE.PiccinniC.PoluzziE.MarchesiniG.De PontiF

According to the Summary of Product Characteristics (SmPC), these include: Nausea (very common: may affect more than 1 in 10 people) Diarrhoea and constipation (very common) Vomiting and abdominal pain (very common) Decreased appetite and dyspepsia (very common) Most gastrointestinal adverse effects are mild to moderate in severity and tend to diminish over time as the body adjusts to treatment

In a systematic review of prospective cKD and MCTKD studies, more than 40 categories of adverse effects were identified, with gastrointestinal (constipation and vomiting), high serum lipid profiles, renal/genitourinary, and skeletal challenges being the most common (36) and often reversible in the short term if the diet is correctly designed

Wound healing and scar quality often determine how youthful and even skin appears, especially after procedures, sun exposure, or years of minor injuries