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Take home message Weight-loss injections are designed as additional tools for weight management interventions and shouldnt be considered lifelong medications

In the PIONEER- 4 trial, semaglutide was not less effective than liraglutide at lowering HbA1c at its daily oral formulation dose [97]

Another meta-analysis of randomized controlled trials found that endothelial function in normal-weight and overweight but not obese patients with type 2 diabetes was significantly improved by supplementation with vitamin E and/or vitamin C (90)