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The design was a blind, randomized clinical study that included twenty-eight subjects

There are better tests that are covered by insurance that can reveal thyroid disease up to a decade before a change in TSH is detected

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Key limitations, however, include dependence on specialized instrumentation (e.g., luminescence photometers), susceptibility to interference from catalysts or enhancers, and pH-dependent mechanistic variations in the luminol reaction (Shahidi and Zhong, 2015)