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Cmo funciona: Acta directamente sobre las mitocondrias, restaurando la eficiencia energtica y reduciendo la inflamacin celular

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53 Generally, the reported K m of PARP1 and CD38 for NAD + are lower than those of the sirtuins, suggesting that elevated activation of PARP1 or CD38 may limit endogenous SIRT activation by reducing NAD + content