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"This narrative is as predictable as it is outdated and false," the company said

A February 2026 Medscape panel discussion on managing constipation in GLP-1 patients, which included specialists from the Cleveland Clinic, identified bulk-forming fiber as a key strategy for patients experiencing constipation, alongside increased hydration, physical activity, and incorporating prebiotic and probiotic foods into the diet

Astragaloside IV inhibits excessive mesangial cell proliferation and renal fibrosis caused by diabetic nephropathy via modulation of the TGF-1/Smad/miR-192 signaling pathway

Am J Physiol Endocrinol Metab (2009) 296:E132634