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As a result, the ETC functioning is disrupted, and ATP content becomes significantly depleted, which breaks down metabolic and ionic homeostasis and activates the degradative enzymes such as nucleases, proteases, and phospholipases [182, 188]

The same applies to adjunctive therapies patients considering NAD alongside peptides should understand the side effects of NAD therapy and discuss interactions with their provider before starting any combination protocol

Samajdar SS, Bhaduri G, Ghoshal PK, Mukherjee S, Pal J, Chatterjee N, Joshi SR (2024) Dual effects of dulaglutide on glycemic control and knee osteoarthritis pain in elderly patients with type 2 diabetes

Those with a BMI of 30 or higher (or 27 or higher if you have certain health issues) will benefit