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may reduce malondialdehyde, a marker of cell damage in the liver Improve blood sugar regulating hormone resistance: low glutathione levels are associated with less fat burning and higher rates of fat storing - supplementing may improve both Increase mobility in peripheral artery disease patients: when the peripheral arteries become clogged with plaque, glutathione may improve circulation, enabling patients to walk longer distances Reduce Parkinson's disease symptoms: intravenous glutathione may help reduce tremors and muscle rigidity Reduce oxidative damage in children with autism: these children have higher levels of oxidative damage and lower levels of glutathione in their brains

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15 Nevertheless, limited cardiovascular and renal outcome data for certain agents, such as oral semaglutide, have constrained their broader clinical application