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A retrospective analysis of 34 patients with overt hepatic encephalopathy found that oral administration of l-carnitine reduced overt hepatic encephalopathy recurrence 55

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position 8, where alanine is substituted by alpha-aminoisobutyric acid and thus increasing resistance to DPP-4 degradation, position 34, where lysine is changed by arginine and thus, preventing wrong binding of C-18 fatty acid, and position 26, where lysine is a acylated with a glutamate spacer 15 to provide specific binding to albumin

Model evaluation The final model was evaluated using goodness-of-fit plots [individual predictions vs