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In addition, this enzyme possesses an N-terminal domain which cleaves Gro3P into glycerol and inorganic phosphate (Pi) (in humans and other organisms, this reaction is catalyzed by a separate glycerol-3-phosphate phosphatase, a reaction also known as glycerol shunt)

To understand the origins of perceived fatigue, it is important to take into account different kinds of potential cellular stresses in periphery, and the information sent to the brain (via the blood circulation, the vagus nerve and sensory inputs)

Updated December 22, 2025

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