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Some have raised concerns about a potential conflict of interest if CMS does eventually cover these drugs under the leadership of Oz, also a former Pennsylvania Senate candidate

[DOI] [PMC free article] [PubMed] [Google Scholar] 45.DAlessio D

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Once activated, these receptors initiate intracellular signaling cascades , such as the PI3K-Akt pathway, which are critical for muscle protein synthesis, cellular growth, and survival (Jones & Clemmons, Endocrine Reviews )