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Introduction Alzheimers disease (AD), a global public health priority, is the most common neurodegenerative disease ( Some human and animal studies show that insulin can accelerate the clearance level of A in the brain and affects the phosphorylation of tau protein, meanwhile, enhances the synaptic activity and plasticity of neurons ( Glucagon-like peptides 1 (GLP-1), derived from intestinal L cells, is an incretin hormone

While uncommon, these serious adverse events require ongoing monitoring and risk assessment, particularly with long-term therapy

This may be uncomfortable at first, but it often improves over time as the body adjusts

Together, we will design a glide path that includes: Deciding whether to continue on a lower maintenance dose, taper off, or pause with a clear restart plan