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Background Cataract is a leading cause of visual impairment and a potential cause of blindness worldwide

In mice, cholesterol-induced stress ligands trigger NKG2D-mediated activation of T cells and IL-17A secretion, which is a key mediator of fibrosis progression ( 4 -induced and MCD diet-induced hepatic injury identified a distinct CCR6 + T cell subset expressing IL-17 and IL-22, which may limit advanced liver fibrosis by inducing HSC apoptosis through a cell-contact-dependent, FasL-mediated mechanism (148) ( Figure 6C )

Diabetes 60: 23082314, 2011