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Methods A literature search was conducted in PubMed and Embase in December 2020 using the search terms scalp AND psoriasis AND (patient preference treatment OR topical OR corticosteroid OR intralesional corticosteroid OR vitamin D analogue OR keratolytic OR salicylic acid OR urea OR methotrexate OR cyclosporine OR acitretin OR etanercept OR adalimumab OR brodalumab OR ixekizumab OR secukinumab OR guselkumab OR infliximab OR certolizumab OR ustekinumab OR risankizumab OR mirikizumab OR apremilast OR phototherapy OR comb OR coal tar)

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84 FR 61158 through 61166

3), including H-bonds with the backbone of S129 ECD , and hydrophobic interactions with D77 ECD , G78 ECD , W79 ECD , Y131 ECD and W128 ECD , consistent with interactions also formed by Pro32 of sCT