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The ability of MEDI4166 to improve glycaemic control in a model of Type 2 diabetes was investigated in male db/db mice following weekly injections of MEDI4166 at 3, 10 or 30 mg/kg over a 4 weeks period

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More serious but less common risks include acute pancreatitis, gallbladder disease, acute kidney injury (usually secondary to dehydration from gastrointestinal losses), and hypoglycemia when used in combination with insulin or sulfonylureas