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2022 AHA/ACC/HFSA guideline for the management of heart failure: Executive summary: A report of the American college of cardiology/American heart association joint committee on clinical practice guidelines

Cheeseman KH, Holley AE, Kelly FJ, Wasil M, Hughes L, Burton G

Caffeine is a gastric irritant that increases stomach acid production and accelerates gastric contractions in ways that conflict with semaglutide's slowing effect