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This process subsequently amplifies the expression of the pro-inflammatory factor NF-B (Mohammed et al., 2025)

This results in prolonged intervals between meals, decreased calorie intake, and delayed gastric emptying, ultimately contributing to significant weight loss one of the drugs most prominent side effects

Factors that may influence weight stability include: nutrition consistency activity levels sleep quality stress levels metabolic health long-term habit formation Weight regain, when it occurs, often happens gradually rather than immediately

After receptor binding, intracellular pathways, including PI3K/Akt/mTOR and MEK/ERK, are activated, contributing to protein synthesis and anabolic signaling