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Phase 3 trials (the TRIUMPH programme) are currently underway to evaluate retatrutide's long-term safety, cardiovascular outcomes, and efficacy across broader patient populations

As of mid-2025, retatrutide is not approved by the MHRA or any other regulatory authority, and all dosing information derives exclusively from clinical trial protocols

These findings support their use as a valuable adjunctive obesity management medication (OMMs) in post-bariatric care, though long-term adherence and cost-effectiveness require further investigation

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