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PMID: 35710796 J Exp Clin Cancer Res GSTK1 suppresses HCC aggravation via L-carnitine metabolism by PGAM5/DRP1 complex-mediated mitochondrial quality control

Neither timing creates a measurable clinical advantage in weight loss, blood sugar reduction, or appetite control based on published trial data

335 Moreover, genomic alterations, such as TMPRSS2-ERG fusion, SPOP mutation, PTEN loss, and CHD1 deletion, are linked to an impaired DNA damage response phenotype, which might increase the therapeutic effectiveness of PARP inhibition

However, in some cases, GSH conjugates can be more reactive than their parental compounds