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In a prospective cohort study involving a clinical population of 1,228 women of childbearing age who were planning to conceive naturally, those who were exposed to SSRIs experienced a 24% reduction in the ability to conceive, with fluoxetine exerting an even more pronounced effect than other SSRIs, as well as a 9% reduction in the incidence of live births

As with all investigational medicines, the safety profiles of cagrilintide and retatrutide are still being characterised through ongoing clinical trials

This allows physicians to fine-tune doses for optimal efficacy while minimizing side effects, potentially improving treatment adherence and outcomes

In the case of weight loss, a physician-supervised weight loss program will be the most effective way to lose weight and keep it off long-term