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A pilot study with twenty subjects and a phase II trial with 65 patients with relapsing MS were enrolled into a 6-month prospective MAD intervention

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Secondary endpoints included changes in CAT phlegm score at 4 and 8 weeks, total CAT score at 4, 8, and 12 weeks, and SGRQ-C at 4, 8, and 12 weeks of treatment compared to the baseline, the satisfaction score and compliance with NAC assessed at 12 weeks, and the association between the satisfaction score and changes in symptom scores