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In the hiPSC-derived microglia, both the carbonyl and azide signals are prominent, and there is a substantial overlap between the two contrasts (Supplementary Fig

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For example, in the SELECT cardiovascular outcome trial studying people with obesity, the extent of weight loss did not correlate with the effects of the drug to reduce heart attack, stroke, and cardiovascular death . Also, another long-acting GLP-1 therapy, albiglutide, [was] withdrawn from the market owing to modest efficacy for reduction of glucose and body weight in people with T2D

DCA, deoxycholic acid