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Superoxide radical production stimulates retroocular fibroblast proliferation in Graves ophthalmopathy

Outside those exceptions, there are no large-scale, long-term human safety trials confirming outcomes for perimenopausal women, which means clinical supervision is not optional

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L-citrulline and citrulline malate supplements are generally safe for healthy individuals, and research has used doses of up to 15g/day without serious adverse effects.15 Like any supplement, even the healthiest individuals might experience some nausea, headaches, or gastrointestinal discomfort when beginning a new regimen