Using positive and negative Notch signaling mRNA scores as previously described (46), we determined high GLP1R expression is primarily associated with a negative Notch regulator mRNA signature (Figure 5C)
When GLP-1 binds to the receptor it stimulates the signaling of cyclic AMP (cAMP) which is responsible for its multiple therapeutic effects
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Experiments in this work were performed with hybridoma supernatant
