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Forearm blood flow of healthy volunteers in response to acetylcholine significantly increased by up to 41% after Pycnogenol intake

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NAD(P)H-induced chemiluminescence and oxidative stress Even if NAD(P)H-induced lucigenin-dependent chemiluminescence does simply reflect the presence of oxidoreductases capable of initiating the redox cycling of the probe, rather than primary O 2 - generation, the diagnostic significance of this activity may still reside in its ability to reflect oxidative stress in human sperm populations [37, 42, 43]