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Possible signs of low Vitamin B12 may include: Fatigue or low energy Weakness Numbness or tingling sensations Difficulty walking or balance issues Mood changes Decreased appetite Digestive symptoms A smooth, tender tongue These symptoms can also be caused by other health conditions, so it is important to speak with a healthcare provider if you have ongoing symptoms or concerns about Vitamin B12 deficiency

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The combination with semaglutide (CagriSema) showed similar tolerability to semaglutide alone

Phase 2 (Q1 2026) will add additional samples (up to 25,000 patients) and more detailed clinical phenotype data to identify predictive safety and tolerability markers and include further validation and refinement of the efficacy signals including: Phasing of drug therapy and impact on efficacy Prediction of high rebound cohorts Evaluation of potential efficacy in other indications PrecisionLife has developed and validated a world-leading combinatorial analytics platform to identify the drivers underpinning over 60 complex chronic diseases