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Ann N Y Acad Sci 1033:4251 Clark RH, Kelleher AS, Chace DH, Spitzer AR (2014) Gestational age and age at sampling influence metabolic profiles in premature infants

The key difference appears to be dosage

8 Assessing predictive capacity: validation against animal models and clinical data The translational promise of OoC technology is fundamentally contingent upon its demonstrated predictive validity for human physiology and pathology