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Both medications have shown significant efficacy in promoting weight loss, but tirzepatides dual action might provide an added advantage for some patients
First, although we identified significant alterations in pathways such as fatty acid -oxidation and PPAR signaling, we lacked direct functional validation through experiments such as mitochondrial respiration assays, gene expression analysis of key regulators (e.g., PPAR target genes), or isotopic tracing of fatty acid oxidation
(PubMed) Kalim S, Clish CB, Wenger J, et al
ZhaoTWuWSuiLHuangQNanYLiuJet alReactive oxygen species-based nanomaterials for the treatment of myocardial ischemia reperfusion injuries
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