Zepbound (tirzepatide): Once-weekly injectable
Take it in the morning on an empty stomach This maximizes absorption, especially in sublingual or capsule forms
Variants were called and filtered for identification of potentially pathogenic variants in candidate genes associated with myopathy and or metabolic disorder based on The Gene Table of Neuromuscular Disorders 2024 [4] (www.musclegenetable.fr/), MitoCarta 3.0 [21] and mtDNA ( Some genes associated with lipid storage myopathy and MADD-like acylcarnitine profile were analyzed in more detail ( PNPLA2 , HADHA , HADHB , ETFA , ETFB , ETFDH , COASY , FLAD1 , ACADS )
These receptors, including B-cell lymphoma 2/adenovirus E1B 19-kDa-interacting protein 3 (BNIP3), BNIP3-like (BNIP3L), FUN14 domain-containing protein 1 (FUNDC1) and the activating molecule in BECN1-regulated autophagy protein 1 (AMBRA1), would bind with LC3 to form autophagosome (Jin et al., 2021)