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In contrast, a test-and-treat approach is recommended for communities at a high risk of stomach cancer and is generally cost-effective in these areas

doi:10.3389/fmicb.2024.1519694 31

During thymic development of nTregs, the CNS2 region undergoes nearly complete DNA demethylation, which ensures the heritable stability of Foxp3 expression

Alternatively (and this is the approach I take for many patients), if you are experiencing significant symptomatic improvement then you can just continue to take the B12 shots indefinitely