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Alternative splicing of CARM1 mRNA generates two isoforms: full-length CARM1 (automethylated) and exon 15 deleted CARM1E15 (automethylation-defective)

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The review thoroughly examines both clinical and practical evidence regarding the use of c-MET inhibitors alongside PD-1/PD-L1 inhibitors, emphasizing that focusing on c-MET with immunotherapy enhances the effectiveness of treating MET tumors exhibiting elevated PD-L1 expression

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