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The STEP-HFpEF trial with GLP-1 RAs semaglutide on HFpEF and obese patients demonstrated enhanced exercise capacity (7.9-point increase in KCCQ-CSS compared to placebo over 52 weeks) but lacked sufficient evidence on cardiovascular endpoints [9,11,12]

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Improving Nutritional Intake and Enhancing Bodily Resistance: After a myocardial infarction, patients often experience reduced appetite and difficulty eating, leading to inadequate nutritional intake