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And that would actually be my third and final point

Liver expressed antimicrobial peptide-2 (LEAP2) is also important in this neuroendocrine system, as it acts as an endogenous GHSR inverse agonist and antagonist [6]

doi: 10.3389/fendo.2020.608733 Received 21 September 2020 Accepted 13 November 2020 Published 14 December 2020 Volume 11 - 2020 Edited by Marian Elizabeth Ludgate, Cardiff University, United Kingdom Reviewed by Utta Berchner-Pfannschmidt, Essen University Hospital, Germany