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PMID 17888957

We highlight the clinical implications of disturbances in physiological brainheart communication for various clinical conditions, including Takotsubo syndrome resulting from emotional stress or from brain disorders, cardiac complications after stroke (so-called strokeheart syndrome), and cognitive dysfunction in patients with cardiac diseases such as heart failure and atrial fibrillation

The key takeaway: if your results seem unusually slow, the issue may not be you or the medication