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Researchers looked into this when they started to notice that coffee seemed to decrease the risk of Type 2 diabetes

Both the semaglutide and tirzepatide shortages that made compounding legally available were declared resolved in 2024 and 2025, the compounding wind-down deadlines have passed, and in April 2026 the FDA proposed closing the remaining legal pathway entirely

According to WHO and other researchers, if nothing is done to curb the problem, the global cost of overweight and obesity could potentially reach US$3 trillion per year by 2030 and more than US$18 trillion by 2060 (WHO 2024