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Wu et al., 2021

It is accepted that an excessive burden of ROS may lead to abnormal cell growth, corresponding changes in intracellular homeostasis and damage to important components of in the cell when the antioxidant defense and/or DNA repair mechanisms cannot balance the excess oxidants [29]

The technique is contraindicated in pregnancy and breastfeeding, in active acne or skin infection, within 6 months of oral isotretinoin, in patients with keloid scarring history, and on anticoagulant therapy without physician clearance

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