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Overall, the mechanisms of semaglutide action can be described as a systemic, weight-focused intervention that targets caloric overload, insulin resistance, and pro-inflammatory adipokine profiles, all of which contribute to the liver pathology of MASH

L-carnitine is an amino acid derivative that acts as a cofactor for fatty acid oxidation, the process of breaking down fatty acids for energy and fuel for the body

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Understanding how these medications work synergistically enables clinicians and patients to make informed treatment decisions aligned with American Diabetes Association guidelines and individual health goals