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Pobierz Kart Charakterystyki substancji chemicznej

Ampo E, Mendes-Silva AP, Goncalves V, Bartley JM, Kuchel GA, Diniz BS

Similarly, a mitochondria-targeted antioxidant molecule reduced pain and improved locomotor and depressive-like behaviours in animals by enhancing SIRT1-mediated antioxidant enzyme activities (SOD and CAT), suppressing proinflammatory markers (TNF- and NF-B) and modulating apoptotic pathways (decreased BAX, increased Bcl-2) [105]