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The litigations further allege that manufacturers failed to adequately warn patients and prescribing physicians about potential risks associated with these drugs despite emerging safety reports, adverse event data, and growing medical concern surrounding gastrointestinal and optic nerve injuries

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9 For example, one longitudinal study reported that probable RBD symptoms disappeared in only 7.5% of PD patients during a four-year follow-up

MAPK has anti-inflammatory effect by inhibiting the activation of nuclear factor kappa-light-chain-enhancer of activated B cells (NF-B) [41,42,43]