topical ghk cu studies Can one peptide dramatically improve skin quality, healing, and tissue regeneration? Dr. Lexy Yoo @lexiyoonp / @ydh_trainingacademy shares a compelling GHK-Cu case and explains why this peptide has become one of the Copper Peptide Before and After:

Animal LD50 studies showed toxic levels around 320 mg/kg body weight, translating to approximately 22,400 mg for a 70 kg human

GHKCu acetate

Understanding and Mitigating 'Copper Peptide Uglies' Some individuals may experience a temporary worsening of skin texture, commonly termed 'copper peptide uglies,' upon initial GHK-Cu introduction, manifesting as mild redness, irritation, or temporary breakouts

The accumulation of GlcCer and GlcSph may disrupt autophagy, impair mitochondria, and promote -synuclein aggregation, although a solid recognized evidence linking decreased GCase activity with substrate accumulation and -synuclein build-up is still lacking (Rocha et al., 2015)