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Excessive pyroptosis leads to rapid rupture of the plasma membrane and the excessive release of proinflammatory cytokines and chemokines, which results in neuroinflammation that triggers a cascade of secondary injuries culminating in neuronal death

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To view a copy of this licence, visit About this article Cite this article Ma, L., He, Y., Xie, H

Age, gender (male, female, other), body mass index (BMI), race (Black or African-American, White or European-American, American Indian or Alaska Native, Native Hawaiian or other Pacific Islander, Asian, other), and sub-group (occasional user, frequent user) were tested as potential covariates in the initial run of each model