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Background Glucagon-like peptide-1 (GLP-1) receptor agonists (RAs) are a class of medications initially developed to treat type 2 diabetes (T2D) and obesity

GLP-1 analogue liraglutide attenuates CIH-induced cognitive deficits by inhibiting oxidative stress, neuroinflammation, and apoptosis via the Nrf2/HO-1 and MAPK/NF-B signaling pathways

While it was originally only used to treat diabetes, tirzepatide has been proven to help people lose weight and is now being prescribed under specific brand names for this purpose

In the long-term, we still have to get more data to figure out how they interact and whether they'll ultimately be synergistic, says Dr