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Any use outside of formally approved clinical trials falls outside the regulatory framework that governs medicines safety in the UK, meaning that individuals who obtain and use retatrutide independently do so without the quality assurance, standardised dosing oversight, and pharmacovigilance protections afforded by licensed medicines

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doi: 10.1172/JCI116186 30 NauckMAKleineNOrskovCHolstJJWillmsBCreutzfeldtW

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