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Gastroenterology 135:100110 Ratziu V, Charlotte F, Bernhardt C et al (2010) Long-term efficacy of rosiglitazone in nonalcoholic steatohepatitis: results of the fatty liver improvement by rosiglitazone therapy (FLIRT 2) extension trial

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By creating a direct, digital channel to the end consumer, these companies are bypassing the long-established and notoriously complex pharmaceutical supply chain, altering the dynamics of drug pricing, brand loyalty, and competitive strategy